Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 6th World Congress on Biopolymers Paris, France.

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Day 1 :

Keynote Forum

Geoffrey R Mitchell

Vice Preseident, Centre for Rapid and Sustainable Product Development, Portugal

Keynote: Rsin based composites, the ultimate green material
Biopolymer Congress 2017 International Conference Keynote Speaker Geoffrey R Mitchell photo
Biography:

Geoffrey Mitchell is passionate about direct digital manufacturing which enables products to be manufactured directly from a digital design without the need for specialist tooling or moulds and the development of novel materials to support the emerging technologies associated with DDM.  He brings a wealth of experience working with polymer based materials both natural and synthetic. He is fascinated by the links between the scales of structures present in all materials and especially biopolymers. He is focused on using processing as a tool to control those scales of structure and hence define the final products of the material.

Abstract:

The current world-wide focus on Climate Change has led to a re-evaluation of all aspects of manufacturing in order to reduce the levsl of carbon dioxide released in to the atmosphere. One approach has been to look to the natural world for the raw material supply on the basis that this is sustainable. This has led to an over simplification of the problem. We still need to minimize the consumption of energy and the inclusion of other non-sustainable sources of raw materials as well as minimizing waste production.  As part of the Research Programme of the Centre for rapid and Sustainable Product Development we have initiated a major strand of work under the umbrella of “Adding value to Forest based Products”: The basic objective is to increase the economic value of forests to ensure their stability and to underpin biodiversity, both objectives are critical to the  Paris Accord (United Nations Framework Convention on Climate Change  dealing with greenhouse gases emissions mitigation, adaptation and finance). Historically, Portugal was the leading exporter in the world of Rosin, a material obtained from pine resin. The pine forests of Portugal are particularly suited to the production of rosin, but in recent years the forests have declined due to poor maintenance and cheap importants of rosin from other countries. Pine resin as tapped from trees contains a mixture of Rosin which itself is a mixture of chemical compounds, water and turpetine. The Rosin is extracted using a particularly eco-friendly process require no other input than the pine resin. The output streams are Rosin, Turpentine and clean water. In order to maintain the green creditionals we are look to products which require no further processing of Rosin both to reduce waste and also minimize energy consumption. To date we have produced an eco-foam, composites and scaffolds for tissue engineering.

Keynote Forum

Florent Allias

Director, Chair Agro-Biotechnologies Industrielles, France

Keynote: Chemo-enzymatic synthesis and polymerizations of bio-based bisphenols derived from ferulic and sinapic acids
Biopolymer Congress 2017 International Conference Keynote Speaker Florent Allias photo
Biography:

Florent Allais (PhD, U. of Florida, 2004) is a Full Professor in Chemistry at AgroParisTech (France) and the Director of the Chair ABI (Industrial Agro-Biotechnologies) in Reims (France). He has presented his research in numerous international conferences, published more than 50 papers in peer-reviewed journals, granted/filed 10 patents, served as reviewer of various journals and as Associate Editor of Frontiers in Chemistry. His research is dedicated to the development of sustainable industrial processes and high valued-added products from agro-resources. More precisely, with expertise in white biotechnologies, green chemistry and downstream processing, his Chair aims at the development of platform molecules like organic acids or phenolics that will be used to create new functional biobased additives, polymers or materials. The chair also aims at the production of valuable sustainable chemical intermediates that can be used in chemistry, in the food/feed industry or in cosmetology as antimicrobials, antioxidants, flavorings or surfactants

Abstract:

Novel renewable bisphenols were prepared through chemo-enzymatic processes under mild conditions from ferulic and sinapic acids.1,2 The enzyme-catalyzed steps have been optimized and lead to high purity grade bisphenols in high to excellent yields.
 The antiradical3/antioxidant4 properties of these bio-based bisphenols were investigated and revealed activities similar or higher than that of current commercially available antiradical/antioxidant additives such as Irganox 1010®. The bisphenols were then used as monomers for the preparation of various types of polymers such as copolyesters,1 polyurethanes,1 polyolefins,1,5 non-isocyanates polyurethanes (NIPUs)6 and epoxy resins7,8,9. The newly obtained materials were then characterized by NMR, GPC, DSC, TGA and DMA. These analyses revealed not only good thermal stabilities but also a broad range of accessible Tg.

Biopolymer Congress 2017 International Conference Keynote Speaker Blanka Rihova photo
Biography:

Blanka Rihova is the president for Institute of Microbiology AS CR, Czech Republic.

Abstract:

DOXHYD-HPMA is doxorubicin bound through hydrazone bond to synthetic polymeric carrier based on N-(2-hydroxypropyl)methacrylamide. It is effective anticancer polymeric prodrug with decreased side-toxicity and the ability to induce immunogenic cancer cell death releasing site-specific tumor antigen and thus acting as endogenous vaccine. We have compared chemo-immunotherapy combination treatment of EL4 T cell lymphoma and 4T1 breast carcinoma with DOXHYD-HPMA and with immune checkpoint blocking anti-CTLA-4 and anti-PD-1 MAbs either alone or in a mixture. To document the role of intestinal microbiota we use germ-free (GF) mice and GF mice monocolonized with Bifidobacterium thetaiotamicron. Acute model of disease when mice are transplanted once with a lethal dose of tumor cells was compared with chronic model where mice are injected six times every other day with a low number of tumor cells. Healthy mice treated with anti-CTLA-4 and anti-PD-1 mAbs did not show any signs of toxicity while significant co-toxicity was seen in cancer-bearing mice. Treatment with checkpoint inhibitors only exerted a very limited cancer response as no long term survivors (LTS) were recorded. On the other hand more than 60% of mice injected also with therapeutically suboptimal dose of DOXHYD-HPMA survived disease-free for more than 100 days. Those suffering from chronic model of cancer showed considerably higher proportion of PD-1+ cells in tumor microenvironment and reacted substantially better to anti-CTLA-4 or anti-PD-1 treatment than mice with the acute model

  • Session 1

Session Introduction

Vakhtang Barbakadze

Tbilisi State Medical University, Georgia

Title: Novel biopolymer with anticancer activity
Speaker
Biography:

Vakhtang Barbakadze has his expertise in isolation and structure elucidation of a new series of plant polyethers, which are endowed with pharmacological properties as anti- cancer agents. Besides, he interested in enantioselective synthesis and biological activities of basic monomeric moiety of these biopolyethers, synthesis of enantiomerically pure epoxides as chiral building blocks for the production of synthetic analogues of natural polyethers. In 1978 and 1999 he has completed his Ph.D and D.Sci. from Institute of Organic Chemistry, Moscow, Russia and Institute of Biochemistry and Biotechnology, Tbilisi, Georgia, respectively. 2006 up to date he is the head of laboratory of plant biopolymers at the Tbilisi State Medical University Institute of Pharmacochemistry. 1996 and 2002 he has been a visiting scientist at Utrecht University (faculty of pharmacy), The Netherlands, by University Scholarship and The Netherlands organization for scientific research  Scholarship Scientific Program, respectively. He has published more than 81 papers in reputed journals.

Abstract:

Within the field of pharmacologically active biopolymers the area  of stable polyethers seems rather  new and  attractive. Caffeic acid-derived  polyethers are  a class of natural products isolated from the  root  extracts   of  comfrey  (Symphytum   asperum)   and   bugloss (Anchusa italica). According  to 13C, 1H NMR, 2D  heteronuclear 1H/13C HSQC and  2D  DOSY experiments  the polyoxyethylene   chain  is  the backbone    of   the   polymer   molecule.    3,4-Dihydroxyphenyl   and carboxyl   groups are   regular   substituents  at  two  carbon  atoms  in the  chain.  The repeating  unit  of  this regular  polymer    is     3-(3,4- dihydroxyphenyl)-glyceric  acid residue. Thus,  the structure of natural polymer under study was found   to be  poly[oxy-1-carboxy-2-(3,4- dihydroxyphenyl)ethylene] or poly[3-(3,4-dihydroxyphenyl)glyceric acid] (PDPGA). PDPGA is endowed with intriguing pharmacological properties as anticomplementary, antioxidant, anti-inflammatory, burn and wound healing and anticancer properties

We examined the efficacy of PDPGA of  S.asperum (PDGPA- SA) and S.caucasicum  (PDGPA-SC)  in androgen-dependent  (LNCaP) and independent (22Rv1  and  PC3) human prostate  cancer  (PCA)  cells. PDPGA-SA  treatment  (100  mcg/ml  for  48h)  decreases  the  live  cell number by 65, 64 and 35% and increases the cell death by 16, 8 and 12  folds    in  LNCaP,  22Rv1  and  PC3  cells,  respectively.  Similarly, PDPGA-SC  treatment  (100  mcg/ml  for  48h)  decreased   the  live  cell number by 87, 25 and 33% and increased the cell death by 19, 10 and 9 folds in LNCaP, 22Rv1 and PC3 cells, respectively

PDPGA   and   its   synthetic    monomer  exerted    anti-cancer efficacy  in vitro and  in vivo  against     human prostate cancer (PCA) cells  via    targeting   androgen    receptor,    cell    cycle    arrest    and apoptosis   without   any  toxicity, together   with   a strong  decrease   in prostate   specific antigen   level in plasma. However, our results showed that anticancer  efficacy  of   PDPGA    is more effective  compared to its synthetic  monomer. Overall, this study identifies  PDPGA as a potent agent against PCA  without any toxicity, and  supports its clinical application

Speaker
Biography:

Stefaan De Wildeman graduated as a Chemical Engineer in Applied Biological Sciences (KULeuven, 1998), and finished his Ph.D. after discovering a new bacterial species dehalorespiring chlorinated organic pollutants in groundwater (Ghent University / Friedrich-Schiller University Jena, 2002).

Since 2002, he joined DSM as an Associate Scientist in the field of Biocatalysis, one of DSM’s world-leading competences. As a Senior Scientist, he has increaslingly explored the potential of biocatalysis to link renewable raw materials to new biobased building blocks for novel materials with added functionality.

In 2013, Stefaan started up a research group and strategic projects on new biobased building blocks at Maastricht University, serving two new Biobased Institutes (Aachen-Maastricht Institute for BioBased Materials (AMIBM) and Institute for Science&Technology (InSciTe)), located at the Brightlands-Chemelot Campus (The Netherlands). Currently, first activities are being framed in start-up dynamics to bring new biobased materials to the market.

Abstract:

A comparative study was prepared investigating the synthesis of polyamides using biobased building blocks derived from sugar beet pulp, namely 2,3;4,5-(di-O-methylene)galactarate (GalXH) and 2,3;4,5-(di-O-isoplopylidene)galactarate (GalXMe) derivatives (Figure 1). Two different approaches towards the synthesis of biobased polyamides were evaluated: melt polycondensation and direct  polycondensation in solution via the phosphorylation technique. The polymerization of GalXMe with diamines results in polymers with narrow dispersity whereas GalXH gives polyamides with broad dispersity. Kinetic studies were performed to understand the different behavior of GalXH and GalXMe during polycondensation. The GalX monomers were combined with linear, cycloaliphatic and aromatic diamines, resulting in amorphous polyamides with glass transition temperatures ranging from 50 °C – 220 °C. The obtained polyamides are stable at elevated temperatures above 300oC. The hydrolytic stability of the acetal groups in the GalX polyamides in different acids (e.g. 5 % acetic acid, 90 % formic acid) was also investigated, revealing the higher acid resistance of GalXH compared to GalXMe.

Figure 1: Structure of GalXH RR(2,3;4,5-(di-O-methylene)galactarate)) and GalXMe RR(2,3;4,5-(di-O-isoplopylidene)galactarate)) with R = -H or R = -CH2CH3; R’ = -H or R’ = -CH3

Speaker
Biography:

L. Amiranashvili has completed his PhD at the age of 27 from I. Javakhishvili Tbilisi State University. She is a research scientist at Tbilisi State Medical University I.Kutateteladze Institute of Pharmacochemistry, department of plant biopolymers. She has published more than 40 papers in reputed journals. Her field of professional interests is Bioorganic and Medicinal chemistry.

Abstract:

Recently high-molecular fractions were isolated from species of Boragenaceae family Symphytum asperum and S.caucasicum. Based on the  IR   and  NMR spectroscopy data,   poly[3-(3,4 dihydroxyphenyl)glyceric  acid]  (PDPGA)  was  confirmed to  be  the major  component of these fractions. This  compound represents a  new class of natural polyethers with a  residue of 3-(3,4 dihydroxyphenyl)glyceric acid as the repeating unit. Polymer  possesses immunomodulatory (anticomplementary), antioxidant, antiinflammatory and  wound-healing  properties.  Phytochemical  investigation  of  roots and stems of Symphytum asperum L. was carried out in order to define starting   substances  for   biosynthesis   of   PDPGA.   The   solid-liquid extraction  technique was  chosen as  the  first step  for  isolation  the compounds probably containing the fragments of PDPGA, followed by the  investigation  using UHPLC-Q-TOF/MS  technique. The  UHPLC-Q- TOF/MS analysis of extracts of S.  asperum roots/stems revealed the presence  of     low   molecular  weight  compounds such as   caffeic, rosmarinic, chlorogenic and salvianolic acids as well several oligomers. The obtained  results show that the comfrey roots/stems can be used as a  source for the isolation of low molecular weight biologically active compounds

Speaker
Biography:

Henri Cramail completed his PhD from the LCPO at the University of Bordeaux 1, in 1990 and a post-doctoral stay at the University of Durham, U.K. Since 1999, he is full Professor of Polymer Chemistry at the University of Bordeaux. In 2004, he was awarded the position of Junior Member of the ‘Institut Universitaire de France’. He was the Director of the Laboratoire de Chimie des Polymères Organiques (LCPO) from 2007 to 2016 and he is today heading the ‘Biopolymers and bio-based polymers’ Team within LCPO. He has published more than 172 papers in reputed journals and, since 2016, is co-editor of the European Journal of Lipid Science and Technology

Abstract:

The aim of this work was to study glycolipids and particularly trehalose esters for the synthesis of new bio-sourced polymers. Trehalose monoesters and diesters were synthesized by two esterification pathways of the primary alcohol of trehalose with different fatty acids. The first synthetic route is a protective group-free esterification using a peptide coupling agent and the second one is a lipase-catalyzed esterification. The self-assembly properties of the trehalose esters were first investigated. While trehalose monoesters showed surfactant properties in water, trehalose diesters appeared to be good gelators for organic solvents and vegetable oils. In a second stage, trehalose diesters were functionalized and polymerized with different strategies. Thus, polyurethanes and poly(hydroxyurethane)s were obtained by polycondensation whereas glyco-polyesters were synthesized by acyclic diene metathesis (ADMET) and thiol-ene polymerizations. The self-assembly properties of these polymers were investigated; in some cases, the latter were able to form some nanoparticles by solvent displacement method.

Speaker
Biography:

Mr Muhammad Mujtaba is working on biopolymers in terms of its production, characterization and possible applications. On chitosan biofilm I am working since last year and I am trying to develop chitosan film with enhanced physicochemical properties such as high thermal stability, good mechanical properties etc. our group is dealing with cellulose, chitin and chitosan for its modification and applications

Abstract:

Nowadays researchers are showing great attention towards the natural polymer or biopolymer based materials such as chitin, chitosan and cellulose. Major reason after this growing interest are the desired properties possessed by such biopolymers including biodegradability, biocompatibility, nontoxicity, antimicrobial features. Production of chitosan based biofilms have been reported in many articles along with their possible applications in several fields such biomedical, food preservation etc. The modification of chitosan film depend upon the nature of application where they are supposed to be applied. Nowadays researcher are focusing more on the production chitosan active food packaging with good barrier, antioxidant and antimicrobial properties. These modification can be achieved by introducing certain active compounds such as plant extracts, essential oils and fruit extracts. Beside its application in food industry, chitosan films can be used    as anti-biofilm drug carrier for wound healing where a prolonged release can be achieved. Keeping all these present applications in mind it can be concluded that still these chitosan films can be modified and enriched further for expanding its application areas. In the field of biomedical these films can be used as coating materials for all the appliances which are using in high temperature areas. This chitosan coating will help in protection of such valuable appliances due to its high thermal stability. But for such applications boosting of physicochemical properties is still needed. In future this can be achieved by incorporating several different compounds.

Speaker
Biography:

Akbar Esmaeili has completed his Ph.D at the age of 47 years from Islamic Azad University, Tehran, Iran. He is the Prof. Department Chemical Engineering North Tehran Branch, Islamic Azad University. He has published more than 100 papers in reputed journals, more 13 books, referee for more 100 paper’s and serving as three editorial board member of repute

Abstract:

Abstract

 

The films based on methylcellulose with biodegradable and antioxidant activity incorporated with nano capsule suspension containing F. angulata essential oil were developed. Oil extraction and identification of F. angulata essential oil compounds was done. Nano capsule suspension containing F. angulata essential oil was prepared by ultrasonic bath. The films were prepared by a casting method in three different ratios. The mechanical properties, colour, light transmission, antioxidant activity and release rate characteristics of the films were studied. The addition of nano capsule suspension to methylcellulose films decreased the thickness, tensile strength but increased the percentage elongation at break (%E) and lightness. High antioxidant activity and a prolonged release of F. angulata essential oil were also reported. Five factors design of Response Surface Methodology were used to optimize the thickness, holding time and anti-oxidant effect of edible film based on methylcellulose incorporated with nano capsule suspension containing F. angulata essential oil. Design of experiments was carried out by the software: Minitab 17 (Sigma package). Optimization of thickness, 2, 2-diphenyl-1-picrylhydrazyl radical scavenging and holding time would yield the best mixture proportions of methylcellulose and nano capsule suspension 30%, 30% and 70%; oil.

  • Session 2

Session Introduction

Maia Merlani

Tbilisi State Medical University, Georgia

Title: New biopolymer from Comfrey: Chemistry and biological activity
Speaker
Biography:

Maia Merlani has completed her PhD from Tbilisi State University. She is a Senior Research Scientist at Tbilisi State Medical University, department of plant biopolymers.. Her field of interest is a chemistry and synthesis of natural compounds. She is the author of more than 55 papers in reputed journals and presentations at 60 international scientific conferences. She was granted Georgian Presidential scholarship for young scientists (1997), NATO scholarship (2002, 2003-2006) and Matsumae International foundation scholarship (2013). She is a member of organizing committee of several international conferences in the field of organic and pharmaceutical Chemistry

Abstract:

Comfrey root has been used as a traditional medicinal plant for the treatment of painful muscle and joint complaints for centuries. Recently biologically active polymer has been isolated from Caucasian species of comfrey Symphytum asperum Lepech. and S.caucasicum Bieb. This polymer - poly[3-(3,4-dihydroxyphenyl)glyceric acid] (p-DGA)  is a representative of a new class of natural polyethers with a residue of 3-(3,4-dihydroxyphenyl)-glyceric acid (DGA) as the repeating unit. P-DGA exhibits high antioxidant, antiimfllamatory, wound healing and anticancer activities. In order to compare biological properties of natural polymer with its synthetic analogues, racemic and pure enantiomeric forms of DGA as well as a methylated analogue of p-DGA - poly(MCDMPO) as a precursor of p-DGA were synthesized. The racemic monomer and its virtually pure enantiomers were synthesized via Sharpless asymmetric dihydroxylation of trans-caffeic acid derivatives using an potassium osmiate catalyst, a stoichiometric oxidant N-methylmorpholine-N-oxide and enantiocomplementary catalysts cinchona alkaloid derivatives (DHQ)2-PHAL and (DHQD)2-PHA as chiral auxiliaries. Poly(MCDMPO) was obtained via ring opening polymerization of 2-methoxycarbonyl-3-(3,4-dimethoxyphenyl)-oxirane (MCDMPO) using a cationic initiator.

 Comparative investigation of antioxidant properties of natural polymer and its monomer revealed that the latter appeared 40 fold active than polymer, however anticancer efficacy of p-DGA against human prostate cancer (PCA) cells is more compared to its synthetic monomer. Poly(MCDMPO) did  not show any activity against PCA.

Speaker
Biography:

Christine Jérôme, full Professor at the University of Liege, has expertise in polymer chemistry and passion in developing biomaterials to improve health and well-being. She developed green strategies for the synthesis, functionalization and processing of polymer materials, degradable or not, to precisely tailor their properties and design supramolecular structures customised to the targeted biomedical application and needs.

Abstract:

Statement of the problem: Polymer hydrogels resemble the natural living tissue due to their high water content and soft consistency. They find many applications in the design and production of contact and intraocular lenses, biosensors membranes, matrices for repairing and regenerating a wide diversity of tissues and organs. Derived from chitin, chitosan [1] is a unique biopolymer that exhibits outstanding properties, beside biocompatibility and biodegradability. Most of these peculiar properties arise from the presence of primary amines along the chitosan backbone. As a consequence, chitosan based hydrogels have shown a great potential for biomedical and pharmaceutical applications. Being degraded in a physiological environment into non-toxic products, chitosan is an outstanding candidate for short- to medium-term applications, such as tissue engineering. In this respect, the preparation of chitosan nanometric fibers mats is highly interesting as such structure mimics the one of skin extracellular matrix. Chitosan nanofibers can be prepared by electrospinning but suffer from weak mechanical resistance if they are used as such. Therefore, strategies allowing to generate chitosan based nanofiber mats exhibiting a mechanical resistance strong enough to be easily handled while keeping the peculiar features of chitosan hydrogels favoring the interaction with cells and soft tissues to provide efficient tissue reconstruction are needed. Findings: (i) combination of electrospinning with the layer-by-layer deposition [2-4] of chitosan, (ii) chemical cross-linking [5-6] of chitosan electropsun nanofibers and (iii) combination of chitosan/poly-caprolactone electrospun multilayers are three strategies that revealed to be efficient to improve the mechanical properties of chitosan nanofiber mats while preserving their biological properties. Conclusion and significance: the control of the nanofiber structure offered by the electrospinning technology makes the developed processes very promising to precisely design biomaterials for tissue engineering as demonstrated by preliminary cell culture tests corroborating the potential use of such systems in wound healing applications

Speaker
Biography:

Fabio Silvestri obtained his PhD in Material Science from University of Milano-Bicocca working on organic electronics (Prof. G. A. Pagani). During the doctoral studies, he also worked at Northwestern University (Prof. T.J. Marks) and Universidad Autonoma de Madrid (Prof Torres) on synthesis and characterization of new materials, and as a post-doctoral fellow at ETH Zürich, in the Prof. F. Diederich group. He then moved to Dow Chemical, working on polyurethane foams, and later on he joined Trocellen as Product Development Manager. He is now Innovation Manager for Trocellen group: his focus is to find new technology driven opportunities.

Abstract:

Chemically cross-linked polyethylene (XLPE) foams can be considered as a commodity material, due to the high volumes and the relatively low price compared to other polymers and foams. Furukawa Electric, the shareholder of Trocellen Group, filed the first patent on this topic in 1968, almost 50 years ago, so we are not talking about an innovative technology. However, polyethylene is still an interesting material with a lot of different application, ranging from insulation to footwear, from automotive to sport and tapes.
Our new vision is “Making a difference – shaping the future”, so we have started to think about a solution to provide a safe and comfortable future with products that make a difference.
For this reason, we have decided to develop Trocellen Bio, a new foam that anticipates a precise request from the market, giving to our customer the opportunity to decide between the normal grade and a more sustainable one. This is because with this approach we can strongly reduce the CO2 emission, something it was never done in this field, at least at industrial scale. The most important thing is we can do it without any compromise in terms of physical-mechanical properties. As you can see in Figure 1, the compression stress at 25 and 50% is the same for the foam produced with Bio-based and petrochemical based

Speaker
Biography:

Dr Joseph Assaad is Professor of Civil Engineering; he earned his Ph.D from Sherbrooke University, Quebec, Canada. His research interests include grinding aids and strength enhancers for clinker, reduction of CO2 emissions during cement production, chemical admixtures for specialty concrete such as SCC, UWC, RAC, HPC, LWC, RCC, etc., injection materials, rheology and thixotropy, formwork pressure, bond to reinforcing steel, composite cementitious systems containing polymers and specialty chemicals, polymerisation of polyvinyl alcohols and styrene butadiene polymers, epoxies for flooring, and hardened concrete properties and durability. Dr Assaad received several local and international awards in the field of cement and concrete technology.

Abstract:

Polymeric latexes such as styrene-butadiene rubber (SBR) and vinyl acrylic homo- or copolymers are widely used in repair and patching works to increase adhesion and bond strengths of cementitious-based materials to various substrates. These have found particular acceptance in reinforced concrete applications due to their superior resistance to corrosion, chloride ion penetration, as well as oxygen diffusion.

 

Limited attempts have been made to develop ready-to-use specialty portland cement possessing improved bond and tensile properties resulting from inter-grinding SBR latexes during clinker processing. This type of cement can be of particular interest in repair and precast applications typically associated with stringent durability and bond to steel requirements. Other relevant applications would be for adhesive and protective cementitious-based construction materials requiring enhanced bond to existing substrates such as rendering and patching mortars, tile adhesives and grouts, and waterproofing slurries.

 

Test results have shown SBR polymers withstand attrition and heat commonly encountered during clinker grinding operations. The so-produced cement possessed particular advantages, but also some weaknesses. For instance, workability of cement together with the flexural and pull-off bond strengths remarkably improved with SBR additions, while in contrast, grindability of clinker and compressive strength were detrimentally affected. The reduced grindability was attributed to the SBR elastomeric binding sites that act as shock dampers to absorb energy and relax stresses at the crack tips, while the drop in compression was related to altered cement hydrating compounds and increased porosity that weaken the cement matrix. Other relevant aspects requiring further investigations include the effect of elastomer latex type, interaction/compatibility with alkanolamine grinding aids, rheology, kinetics of hydration reactions, as well as validation on real-scale industrial mills.

Speaker
Biography:

Zhili Li is currently a Professor in Chemical Engineering at Guangxi University, Nanning, China. Li received his Ph.D degree from South China University of Technology in Chemical Engineering in 2009. During 2014-2017, he worked as a Visiting Scholar in School of Engineering & Applied Sciences at Harvard University. His research interests are focused on the development of advanced materials using natural polymer lignin as building blocks and its applications for different areas. Prof. Li has published more than 30 papers in peer-reviewed journals, granted 8 patents, and served as a reviewer of various journals in Chemical Engineering and Materials Science.

Abstract:

Nanomaterials have gained a great deal of interest in environmental remediation because of their higher surface-to-volume ratio and higher surface reactivity properties than the bulk. However, nanomaterials are considered harmful as they become transparent to the cell-dermis. Toxicity of nanomaterials also appears predominant owing to their high surface area and enhanced surface activity. The future demand for nanomaterals with diverse functionalities is expected to increase significantly and alternative raw materials have to be identified and implemented to reduce their production cost and minimize their environmental impact. Renewable raw materials from biomass sources are attractive for producing low-cost, totally green nanomaterials, due to their unique characteristics including abundance, biocompatibility/ biodegradability and renewability. Here, we demonstrated a functionalized nanomaterial derived from lignin, the second most abundant natural polymer on the Earth. The fabricated functionalized nanolignin was characterized by FT-IR, SEM-EDS, BET, and XPS analyses. The adsorption performance to heavy metals on the nanolignin was also investigated. As a result, it showed a very high selectivity to silver (kAg/Pb=32.7; kAg/Cu=13.8) than lead and copper ions from aqueous solutions. Moreover, the silver-loaded nanolignin showed a high antibacterial activity to Escherichia coli and Staphylococcus aureus.

 

Speaker
Biography:

Prof. Qigu Huang, Ph.D. obtained in Zhongshan University, China, under supervised by Prof. Shang-An Lin in 2000, and had postdoctoral fellows in RIPP, SINOPEC, Alcala University, Spain and Sussex University, UK. He has his expertise in polyolefin materials and organometalic catalyst. He has focused on the new methodologies for olefins controlled polymerization, new methods for the efficient use and high value transition of the fossil resources and biomass, the design and synthesis of new catalysts and high performance/functional polyolefins, and high performance/functional composites and hybrid materials based on polyolefins.

Abstract:

Copolymers of N-acetyl-O-(ω-alkenyl)-L-tyrosine ethyl esters with ethylene were synthesized by the titanium complexes. The structures and properties of the obtained copolymers were characterized by FT-IR, 13C NMR, GPC, DSC and water contact angle. The results indicated that the obtained copolymers had high weight average molecular weight of 2.85× 105 g mol-1 and high incorporation ratio of N-acetyl-O-(but-3-enyl)-L-tyrosine ethyl ester up to 2.65 mol% within the copolymer chain uniformly. The units of the comonomer were isolated within the copolymer chains. The insertion of the polar comonomer into copolymer chain can
effectively improve the hydrophilicity of copolyethylene

Speaker
Biography:

Mr. Oliver Meldrum obtained a Bachelor of Science (Hons.) at the Australian National University and is currently undertaking a PhD at the University of Queensland. Oliver’s major research interest concern understanding the structure and rheology of mucus that lines the internal surfaces of the body and a focus on what food structure and food components are able to modify the physical and selective barrier properties of intestinal mucus

Abstract:

The adherent mucus layer is a vital component of the body’s epithelial surfaces. Mucus assembly is characterised by the presence of multiple levels of mucin structure at different length scales. This gives mucus its unique set of rheological and barrier properties that enable it to establish an effective physical and selective diffusion barrier as well as to hydrate the underlying epithelium. The rheological and structural characteristics of intestinal mucin, the functional component of the mucus layer and their interaction with cell wall components, that are liked with a number of health benefits are investigated. Biochemically well characterised porcine intestinal mucin has been utilised as a model for human mucins to characterise their viscoelasticity, structure and dynamics as a function of concentration, pH and Ca2+. The mesoscopic forces that mediate mucin were investigated using reducing, chaotropic and chelating agent agents. The rheological and structural characteristics of mucin were investigated using a combination of particle tracking microrheology, narrow gap oscillatory shear and high shear rheometry, and confocal microscopy. In this work, the complex rheological properties of the gelling mucus preparation are in a striking contrast with that of extensively purified mucin. The role and importance of non-mucin components have been elaborated, and the contribution to such interactions as hydrogen bonding, Ca2+-mediated links, and disulfide bonds has been evaluated. These bulk viscoelastic values are dominated by the elastic moduli, while the microrheological response is less dominant. We compare the ability of soluble dietary fibers and plant cell walls to alter the rheological and diffusion properties of purified intestinal mucin. Altering the organisation of mucus as a result of interactions with food components such as plant cell walls and soluble dietary fiber will provide new insights into the ways in which these nutritional components affect the barrier properties of mucus, and provide a possible underpinning mechanism contributing to their health promoting properties.