N.Gorgaslidze has completed her PhD at the age of 37 years from Saint-Petersburg State Chemical-Pharmaceutical Academy. She is the director of TSMU I.Kutateladze Institute of Pharmacochemistry and professor at the department of Social and Clinical Pharmacy at Tbilisi State Medical University. She has published more than 80 papers in reputed journals.
Enzymes as drugs are used for the treatment of many diseases. Nowadays, the number of enzyme containing preparations is not so great. This is due to several reasons: lack of resources, high price, immunogenic problems and low stability. The present work describes development of new drug forms - gels, containing bromelain and papain as well initial studies of standardization of the fruit bromelain and stem bromelain from the pineapple (Ananas comosus L.) and the comparative characterization of their physical-chemical properties. Particularly, influences of concentrations of cystein and casein on the speed of hydrolyze, dependence of casein lysis on concentration of bromelain, optimal parameters of pH and temperature were studied. The bases for the gels, which determine the optimal resorption and stability of the biological active compounds were selected
J. Rodolfo Rendón-Villalobos has his expertise in development and obtaining of Biopolymers that are used to produce composites biodegradables for its potential application in the packaging industry, with the intention of reducing the use and gradually replace conventional polymers to help and try to solve the pollution problems. Coordinates the evaluation of the biopolymers and composites in its structural characteristics as spectrophotometry FT-IR, SEM, XRD; as well as Biodegradation studies, Rheological and Thermal analysis
The need to reduce the use and gradually replace conventional polymers to help and try to solve the pollution problems, has driven research into the development of packaging with a lower environmental impact, which retain the physical and mechanical properties necessary for the preservation of food. In this sense, to achieve this goal it has been emphasized that the use of biopolymers, as they come from renewable sources and characteristics necessary for the manufacture of food packaging. The main aim of this work was to obtain bio-composites based on PLA/PCL/essential oil. Methodology: Response surface using a multiple factorial design with level 2k, was employed to study and investigate the individual and interactive effects of process variables on response variables. The independent variables X1, X2, X3; (PLA, PCL, and essential oil) and the response variables (dependent variables Y): stress fracture, % elongation and Young´s modulus were chosen. Results: The quadratic regression coefficient showed a highly significant at 95 % confidence level (p < 0.05). The ideal conditions were 80 %, 20 % and 10 % for PLA/PCL/cinnamon oil; exhibiting optimum values for stress fracture, % elongation and Young´s modulus of 60.88 Mpa, 267.64 % and 603 Mpa, respectively. All the dependent variables were in favourable range, wherewith was obtained water vapour permeability (WVP) values of 5.73 x 10-13 g m-1 s-1 Pa-1 for the optimized bio-composite. Conclusion & Significance: The bio-composite with desirable bio-mechanical and barrier properties, can be applied as coating in the food packaging industry.